Chapter 10: Molecular Biology of the Gene.

Introduction to the chapter.  You will be reminded of the macromolecules and the monomers.  The basis of this chapter will be about Nucleic acids; DNA and RNA.  We will also examine viruses.

Genetic Test

Multiple choice test on Chapters 8 and 9

Chapter 9 Packet

Chapter 9 Packet is due.

End of Chapter 9

You will watch the video clip, One Wrong Letter. The video is about about a real life experience of
Tay Sachs disease.  Click on the link below to view.
 
One Wrong Letter

We will also have some final thoughts about the chapter and answer questions about the worksheets.

Fingerprints and Incomplete Dominance Lab

The class will grade the sex-linked, hemophilia work sheet.
We will also discuss one of the article from the Wall Street Journal's Opinion section from 2/19/2019

Lab: You will name the fingerprint patterns, and then find each of the three types from yourself from others.

ABO Blood Types

People with blood type AB are considered universal recipients.
People with blood type O are considered universal donors.


Definition: An antigen is a substance that stimulates the production of antibodies when introduced into the body. Antigens include toxins, bacteria, viruses and other foreign.  The carbohydrates found on the red blood cells, A and B blood types are antigens.
The Rh blood grouping is also an antigen.  However, this antigen is made of protein.

Antibody: any of numerous proteins produced by white blood cells in response to the presence of specific foreign antigens. Antibodies attach to antigens and deactivate them.

Worksheets

Thursday, February 14, 2019

You will have the opportunity to do two other worksheets to offset the grade due to not paying attention to the details. 

Happy Valentine's Day 

   Have a great 4 day weekend.

Sex-linked and Autosomal Worksheets

You will work individually to figure out the genotypes and phenotypes in the pedigree chart and Punnett square.

Sex-linked genes exhibit a unique pattern of inheritance

Sex-linked Recessive Inheritance



Some examples of other sex-linked genes are:
1) Deafness (congenital) ( some other forms of deafness too)
2) Red green colorblindness
3) Mental retardation
4) Short stature (idiopathic familial)
5) Melanoma

Lab: Determination of Genotypes from Phenotyoes in Human

You will work in groups of 4 to determine you genotypes by examining your phenotypes.
In addition, we will look at some of the common traits to see which ones are dominant.

Also, we will review the dihybrid worksheets from class on Friday.

Dihybrid Cross

You will work independently on the worksheets to show your understanding of dihybrid cross. 
You will read in the information given and then state the genotypes of the Parent, F1, and F2 generations. 

You will also be required to write the phenotypic and genotypic ratios.

Dihybrid Cross

Gregor Mendel: The Father of Genetics

 You will be taught how to do a Punnett Square for a dihybrid cross. The results will support the hypothesis that each pair of genes segregates independently during gamete formation.

 

Autosomal Disorders in Humans

Wednesday, February 6, 2019
The class will examine some of the common autosomal disorders, the major symptoms, incidence and the members of the popular affected:

The Recessive Disorders:
Albinism
Cystic fibrosis
Sickle Cell anemia
Tay Sachs Disease

The Dominant Disorders:
Achondroplasia - Dwarfism
Huntington's Disease
Hypercholesterolemia

Pedigree Practice

You will work individually to figure out the genotypes of members of the pedigree charts.
No questions will be allowed.

Karotyping Lab Continued and Grading the rest of Chapter 8

The class will complete the grading of the last section of Chapter and complete the lab. 
The final day to turn in the lab will be on Tuesday, February 5, 2019.  No more class time will be spent to complete it.

Karyotyping Lab

You will examine the chromosomes of your fictional patients to test for abnormalities